Ruthenium tris(2,2?-bipyridyl) complex encapsulated in nanosized faujasite zeolite as intracellular localization tracer

Designing zeolites for medical applications is a challenging task that requires introducing new functionalities without altering the intrinsic properties such as morphology, crystallinity, colloidal stability, surface charge, and porosity. Herein, we present encapsulation of luminescent ruthenium-tris(2,2?-bipyridyl) complex in faujasite (FAU) zeolite nanocrystals (Ru(bpy)3-FAU) their use an intracellular localization tracer. Upon exciting Ru(bpy)3-FAU at 450 nm, sample gives rise to orange-red emission 628 thus permitting its cellular imaging nanoparticles. The nanosized characterized terms size, porosity, thermal sorption capacity. potential toxicity on U251-MG glioblastoma cells was evaluated. A safe concentration (50–100 µg/ml) identified. ruthenium confined allow with main accumulation cytoplasm. candidate biological being stable, safe, capable loading respiratory gases, easily probed owing properties.